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SmarT is an investigational drug being evaluated in a clinical trial for the first-line treatment of locally advanced unresectable or metastatic, HER2 negative gastric / gastroesophageal junction adenocarcinoma (GEJ). It is administered as part of a combination regimen that includes a PD-1 antibody, chemotherapy (oxaliplatin and S-1), and low-dose radiotherapy. The specific mechanism of action for SmarT itself is not detailed in the provided context, but it is intended to be used in conjunction with established cancer therapies.
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