Drug intelligence / Profile preview

SMU-Y6

Development stage
Unknown
Lead developer
Southern Medical University
01

Overview

SMU-Y6: sourced facts only. name: "SMU-Y6 could stabilize TLR2 and bind to TLR2 protein with a Kd of 0.18 μmol/L." [PMID:37719381]; target: "SMU-Y6 could stabilize TLR2 and bind to TLR2 protein with a Kd of 0.18 μmol/L." [PMID:37719381]; developer: "Guangdong Provincial Key Laboratory of New Drug Screening and NMPA Key Laboratory for Research and Evaluation of Drug Metabolism, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China." [PMID:37719381]; stage: "Additionally, SMU-Y6 could efficiently reverse the M1 phenotype macrophage polarization, reduce the production of cytokines as well as infiltration of neutrophiles and alleviate the local inflammation in mice with acute paw edema and colitis." [PMID:37719381]

02

Targets

TLR2 (Toll-like Receptor 2)

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