Drug intelligence / Profile preview

SNA018

Development stage
Unknown
Lead developer
SmartNuclide
Modality
Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

SNA018 is a HER2-targeted radiopharmaceutical diagnostic imaging agent developed by SmartNuclide through a licensing agreement with Hober Biotech AB. It is designed for positron emission tomography (PET) imaging to detect and monitor tumors that overexpress the Human Epidermal Growth Factor Receptor 2 (HER2), primarily in patients with breast cancer and gastric cancer. The agent consists of a high-affinity targeting moiety labeled with radionuclides such as Gallium-68 (68Ga) or Fluorine-18 (18F, sometimes referred to as 68F in specific pipeline contexts). By binding specifically to the HER2 receptor, SNA018 enables non-invasive, whole-body assessment of HER2 expression, which helps clinicians identify patients suitable for HER2-targeted therapies and monitor treatment response, addressing the challenges of tumor heterogeneity often missed by traditional biopsies.

Other names
SNA018-SmartNuclide-HER2-radiopharmaceuticalSNA-018-SmartNuclide-HER2-radiopharmaceuticalSNA 018-SmartNuclide-HER2-radiopharmaceuticalHER2-targeted radiodiagnostic agentHER-2-targeted radiodiagnostic agentHER 2-targeted radiodiagnostic agent
02

Targets

ERBB2 (Erb-b2 receptor tyrosine kinase 2)

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