Drug intelligence / Profile preview

Snigzole D

Development stage
Phase 4
Lead developer
Snig Pharmaceuticals
Modality
Small Molecules
Administration
Oral
01

Overview

Snigzole D is a fixed-dose combination drug product developed and marketed by SNIG Pharma. It is formulated as a capsule containing pantoprazole (40 mg) and domperidone (30 mg). Pantoprazole is a small molecule proton pump inhibitor that irreversibly binds to the H+/K+-ATPase enzyme system (the proton pump) of the gastric parietal cell, effectively suppressing the final step of gastric acid production. Domperidone is a dopamine D2 receptor antagonist that acts as a prokinetic agent, increasing lower esophageal sphincter pressure and enhancing gastric emptying. This combination is primarily used for the management of gastroesophageal reflux disease (GERD), peptic ulcers, and other acid-related gastrointestinal disorders where both acid suppression and improved motility are clinically indicated. The product is approved and marketed in India.

Brand names
Snigzole D
Other names
domperidone + pantoprazole
02

Targets

DRD2 (Dopamine D2 Receptor)ATP4A (Potassium–transporting ATPase alpha chain 1)

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