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sodium + potassium + magnesium + calcium + glucose
- Development stage
- Phase 4
- Modality
- Small Molecules
- Administration
- Intravenous
01
Overview
This is a sterile intravenous solution containing the electrolytes sodium, potassium, magnesium, and calcium, along with glucose as a carbohydrate source. It is formulated to replenish fluids and essential electrolytes in patients experiencing dehydration or electrolyte imbalances due to conditions such as vomiting, diarrhea, shock, or other causes of fluid loss. The inclusion of glucose provides an immediate energy source in addition to supporting cellular uptake of electrolytes. The mechanism of action involves restoring normal plasma concentrations of these key ions—sodium (Na⁺), potassium (K⁺), magnesium (Mg²⁺), and calcium (Ca²⁺)—which are critical for nerve conduction, muscle contraction (including cardiac function), acid-base balance, and overall cellular homeostasis. Glucose serves as a metabolic substrate for energy production[5][8].
- Other names
- sodium potassium magnesium calcium and glucose injection
02
Targets
CaSR (Extracellular calcium-sensing receptor)SLC2A4 (Solute carrier family 2 facilitated glucose transporter member 4)CaV (Voltage-gated calcium channel protein complex)Kir (Inward-rectifier potassium channels)NaV (Voltage-gated sodium channels)CaV3 (Caveolin-3)KCNQ1 (Potassium voltage-gated channel subfamily KQT member 1)
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