Drug intelligence / Profile preview

sodium acetate + sodium gluconate + magnesium chloride + sodium chloride + potassium chloride

Development stage
Unknown
Lead developer
Baxter Healthcare Corporation
Modality
Small Molecules
Administration
Intravenous
01

Overview

A sterile, isotonic, physiologically balanced **intravenous crystalloid electrolyte solution** containing sodium acetate, sodium gluconate, magnesium chloride, sodium chloride, and potassium chloride. This Baxter product is marketed as **Plasma-Lyte A** and is used in adults and pediatric patients as a source of water and electrolytes for hydration and correction of extracellular fluid and electrolyte deficits, and as an alkalinizing agent. Its pharmacologic effect is replacement of key extracellular electrolytes and volume, while acetate and gluconate are metabolized to bicarbonate precursors that help buffer metabolic acidosis. It is a **small molecule electrolyte combination product**, not a biologic, and is also closely related to electrolyte irrigation solutions used for general irrigation, rinsing, and washing, although the exact drug here is the injectable multi-electrolyte formulation.

Brand names
Plasma-Lyte APLASMA-LYTE A Injection pH 7.4
Other names
Plasmalyte Amultiple electrolytes injection type 1multiple electrolytes injection type 1 pH 7.4

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