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sodium adenosine nucleonate
- Development stage
- Unknown
- Lead developer
- MIPO Clinic
- Modality
- Small Molecules
- Administration
- Intravenous
01
Overview
Sodium adenosine nucleonate (Adenorine) is an immunostimulating agent being evaluated by the MIPO Clinic as an adjunctive mitochondrial immunotherapy for patients with metastatic colorectal cancer. It functions by activating the monocyte-macrophage system, enhancing cellular repair and regeneration, and reducing inflammatory symptoms. In clinical trials, it is used in combination with the FOLFOX chemotherapy regimen to improve treatment efficacy, enhance patient quality of life, and mitigate chemotherapy-induced toxicities, specifically by addressing neutrophil mitochondrial dysfunction. The drug is also known for its ability to stimulate lymphocyte activation and accelerate wound healing processes in other clinical contexts.
- Brand names
- Adenorine
- Other names
- sodium nucleonateDNA-Naadenosine nucleonate sodium
02
Targets
ADORA2A (Adenosine A₂A Receptor)ADORA3 (Adenosine A3 receptor)ADORA2B (Adenosine A2B receptor)
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