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Sodium alginate
- Development stage
- Phase 4
- Modality
- Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Small Molecules, Non-biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Injectable Hydrogels → Hydrogel Systems → Drug Delivery Systems
- Administration
- Oral
01
Overview
Sodium alginate is the sodium salt of alginic acid—a hydrophilic polysaccharide extracted from brown seaweed. It is widely used as a stabilizer, thickener, and emulsifier in food products and as an excipient in pharmaceuticals[2][3]. In medicine—particularly for gastroesophageal reflux disease (GERD) and heartburn—sodium alginate acts by forming a viscous gel or "raft" upon contact with gastric acid. This raft floats on top of stomach contents to create a physical barrier that prevents reflux of gastric acids into the esophagus[1][4][5]. Sodium alginate is also found in antacid formulations such as Gaviscon. Its mechanism does not involve systemic absorption but rather mechanical protection via gel formation.
- Brand names
- AlginKelginProtanal
- Other names
- sodium alginatealginic acid sodium salt
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