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sodium alginate + calcium carbonate + magnesium carbonate + hyaluronic acid + aloe vera

Development stage: Unknown
Lead developer: Uriach
Modality: Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration: Oral

Overview

This therapeutic combination is a multi-component formulation designed for the symptomatic management of gastroesophageal reflux disease (GERD) and gastric hyperacidity. It operates through a triple mechanism of action: sodium alginate reacts with gastric acid to form a physical 'raft' or barrier that floats on top of the stomach contents, mechanically preventing the reflux of acid and bile into the esophagus. Calcium carbonate and magnesium carbonate act as antacids, neutralizing excess gastric acidity to provide rapid relief from heartburn. Additionally, hyaluronic acid and aloe vera provide a muco-protective effect by coating the esophageal and gastric mucosa, shielding the tissue from chemical irritation and facilitating the healing of acid-induced damage. The product is typically administered as an oral tablet designed to dissolve in the mouth to maximize mucosal contact.

Brand names: Almabian
Other names: Alginate/Antacid/Muco-protective complex

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