sodium benzoate

Sodium benzoate is a synthetic compound with the chemical formula C7H5NaO2, produced by combining benzoic acid with sodium hydroxide. It is widely used as an antimicrobial preservative and flavoring agent in the food industry and as a tablet and capsule lubricant in pharmaceutical manufacturing[2][4]. Medically, it is used to treat elevated blood ammonia levels (hyperammonemia), particularly in patients with urea cycle enzyme deficiencies, often as part of combination therapy (e.g., with sodium phenylacetate)[1][3]. Sodium benzoate acts by conjugating with glycine in the liver to form hippuric acid, which is then excreted via urine[4]. It also exhibits antifungal and antibacterial properties due to its ability to inhibit the growth of bacteria, yeast, and mold[5]. The compound has been studied for potential therapeutic effects in conditions such as schizophrenia, depression, pain syndromes, autism spectrum disorders, and neurodegenerative diseases[1][5].

Brand names

Ammonul

Other names

E211E-211E 211benzoate of soda