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Sodium bicarbonate is an inorganic compound used as a medication primarily to treat metabolic acidosis, which can occur in conditions such as severe renal disease, uncontrolled diabetes, circulatory insufficiency due to shock or dehydration, and lactic acidosis. It is also used for the relief of heartburn and acid indigestion by neutralizing excess stomach acid. In cases of certain drug intoxications (e.g., barbiturates, salicylates), it helps alkalinize urine to enhance toxin elimination. Mechanistically, it acts as a systemic alkalinizer by increasing blood bicarbonate concentration and buffering excess hydrogen ions to raise blood pH[1][2][3][4][8].
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