Drug intelligence / Profile preview

sodium bicarbonate

Development stage
Approved
Lead developer
Huazhong Pharmaceutical
Modality
Small Molecules
Administration
Oral, Intravenous, Topical
01

Overview

Sodium bicarbonate is an inorganic compound used as a medication primarily to treat metabolic acidosis, which can occur in conditions such as severe renal disease, uncontrolled diabetes, circulatory insufficiency due to shock or dehydration, and lactic acidosis. It is also used for the relief of heartburn and acid indigestion by neutralizing excess stomach acid. In cases of certain drug intoxications (e.g., barbiturates, salicylates), it helps alkalinize urine to enhance toxin elimination. Mechanistically, it acts as a systemic alkalinizer by increasing blood bicarbonate concentration and buffering excess hydrogen ions to raise blood pH[1][2][3][4][8].

Brand names
Arm & Hammer Baking SodaHumco Sodium BicarbonateMedis Sodium BicarbonateRapidol Sodium BicarbonateNeogenVet Sodium BicarbonateThe Itch Eraser SensitiveBrioschi Effervescent Antacid
Other names
baking sodasodium hydrogen carbonatemonosodium carbonatehydrogen carbonate sodiumsodium hydrogencarbonatenatrii hydrogenocarbonasnatrum bicarbonicum

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