Drug intelligence / Profile preview

sodium cellulose phosphate

Development stage
Unknown
Lead developer
Mission Pharmacal
Modality
Device-based Delivery → Drug Delivery Systems, Small Molecules
Administration
Oral
01

Overview

Sodium cellulose phosphate is an ion-exchange resin used primarily to prevent the formation of calcium-containing kidney stones in patients who absorb too much calcium from their food. It is also used to treat hypercalcemia and hypercalciuria. The drug works by binding with calcium and other divalent cations in the gastrointestinal tract, thereby reducing their absorption into the bloodstream and ultimately decreasing urinary excretion of calcium. This mechanism helps lower high levels of urinary calcium, which can contribute to kidney stone formation. Sodium cellulose phosphate is not absorbed systemically; its action is localized within the gut. The most well-known brand was Calcibind, developed by Mission Pharma, but it has been removed from the market for unspecified reasons[1][2][3][5].

Brand names
Calcibind
Other names
sodium cellulose phosphatecellulose sodium phosphate
02

Targets

MG (Mycoplasma gallisepticum)CaSR (Extracellular calcium-sensing receptor)

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