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sodium chloride + calcium chloride + dextrose monohydrate + sodium lactate + magnesium chloride
- Development stage
- Approved
- Lead developer
- Fresenius Medical Care
- Modality
- Small Molecules
- Administration
- Intraperitoneal
01
Overview
sodium chloride + calcium chloride + dextrose monohydrate + sodium lactate + magnesium chloride is a multi-component peritoneal dialysis solution used for renal replacement therapy in patients with renal failure requiring peritoneal dialysis. It is marketed in products such as Delflex and Dianeal. Dextrose monohydrate functions as the osmotic agent that creates a transperitoneal osmotic gradient to promote ultrafiltration and fluid removal, while sodium, calcium, magnesium, and chloride provide electrolyte content and sodium lactate serves as a metabolizable buffer that helps correct acid-base abnormalities. This product is not a targeted small molecule or biologic; its therapeutic effect is primarily physicochemical within the peritoneal cavity rather than mediated by a discrete molecular target.
- Brand names
- DelflexDianeal
- Other names
- peritoneal dialysis solutionlactate-buffered dextrose peritoneal dialysis solutionhypertonic peritoneal dialysis solution
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