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TPN Electrolytes is a fixed-dose **intravenous multi-electrolyte additive** containing sodium chloride, calcium chloride, magnesium chloride, sodium acetate anhydrous, and potassium chloride. Developed by Hospira and marketed within Pfizer's portfolio, it is used as a supplement to parenteral nutrition solutions, particularly concentrated dextrose and amino acid admixtures administered by central venous infusion, to help maintain or prevent disturbances in electrolyte and acid-base homeostasis in adults receiving total parenteral nutrition. Its pharmacologic effect is replacement and maintenance of essential physiologic electrolytes: sodium, potassium, calcium, and magnesium directly replenish extracellular and intracellular ionic requirements, while acetate serves as a bicarbonate precursor that supports metabolic buffering. The product is a concentrated sterile solution intended for intravenous use only after dilution and thorough mixing in nutritional solutions.
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