Drug intelligence / Profile preview

sodium chloride + calcium chloride + sodium lactate + dextrose monohydrate + potassium chloride

Development stage
Approved
Lead developer
ICU Medical
Modality
Small Molecules
Administration
Intravenous, Parenteral
01

Overview

**Sodium chloride + calcium chloride + sodium lactate + dextrose monohydrate + potassium chloride** is a sterile intravenous crystalloid electrolyte and carbohydrate combination product corresponding to a potassium-containing dextrose lactated Ringer's solution. It is used as a parenteral source of water, electrolytes, and minimal calories, and as an alkalinizing agent for replacement of extracellular fluid and electrolyte losses in adults and pediatric patients. Its pharmacologic effect is not mediated through a single receptor target; instead, the solution restores extracellular fluid volume and electrolyte composition, potassium chloride supplements potassium, dextrose provides carbohydrate calories, and sodium lactate is metabolized to bicarbonate to help buffer metabolic acidosis. Public labeling and product information identify products of this exact composition as marketed intravenous infusion solutions from Hospira and ICU Medical.

Brand names
Lactated Ringer's and 5% Dextrose InjectionLactated Ringer's and Dextrose 5% InjectionPotassium Chloride in Lactated Ringer's and Dextrose 5% Injection
Other names
sodium chloride + calcium chloride + sodium lactate + dextrose monohydrate + potassium chloridelactated ringer's and dextrosedextrose in lactated ringer'sd5lrd-5lrd 5lrd5 lactated ringer's

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