Drug intelligence / Profile preview

sodium chloride + sodium acetate + sodium gluconate + magnesium chloride + potassium chloride

Development stage
Unknown
Lead developer
Baxter Healthcare Corporation
Modality
Small Molecules
Administration
Intravenous
01

Overview

A sterile, isotonic **balanced crystalloid electrolyte solution** containing sodium chloride, sodium acetate, sodium gluconate, magnesium chloride, and potassium chloride. Intravenous presentations, including Plasma-Lyte A and Plasma-Lyte 148, provide water and physiologic concentrations of sodium, potassium, magnesium, chloride, acetate, and gluconate for extracellular-fluid replacement, hydration, and electrolyte replenishment. Acetate and gluconate are metabolized with hydrogen-ion consumption, producing an alkalinizing effect. Labeled uses include replacement of acute extracellular-fluid losses associated with surgery, trauma, burns, or shock, and adjunctive restoration of circulating volume with moderate blood loss. Equivalent ingredient-set products are also marketed as irrigation solutions, including Physiolyte and PhysioSol, which are not intended for usual parenteral administration. ([dailymed.nlm.nih.gov](https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=6ec9e61c-2c26-402f-8604-f446b2e34058))

Brand names
Isolyte SNormosol-RPlasma-Lyte 148Plasma-Lyte148Plasma-Lyte-148Plasma-Lyte APhysiolytePhysioSol
Other names
Multiple Electrolytes Injection Type 1, USPsodium chloride + sodium gluconate + sodium acetate + potassium chloride + magnesium chloride

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