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**Sodium chloride + sodium acetate anhydrous + sodium gluconate + potassium chloride + magnesium chloride** is a sterile balanced crystalloid intravenous electrolyte solution marketed as **Normosol-R**. It contains sodium, chloride, potassium, magnesium, acetate, and gluconate at concentrations intended to approximate extracellular fluid and support restoration of intravascular and interstitial volume following acute extracellular fluid loss. Acetate and gluconate are metabolizable bicarbonate precursors that provide an alkalinizing effect. The product is used for fluid and electrolyte replacement in settings including surgery, trauma, burns, shock, and moderate blood loss; it is not a substitute for blood products during uncontrolled hemorrhage or severe red-cell depletion. Current US labeling identifies ICU Medical as the packager and manufacturer. ([dailymed.nlm.nih.gov](https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0e089a44-0cee-4804-8f6f-8508508ddb5c))
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