Sodium chloride + sodium citrate

Sodium chloride + sodium citrate is a combination of two electrolytes used primarily to replace fluids and minerals lost due to diarrhea and vomiting, helping prevent or treat dehydration[1]. Sodium chloride provides essential sodium ions, while sodium citrate acts as an alkalinizing agent by being metabolized to bicarbonate, which helps neutralize excess acid in the blood and urine. This combination supports normal body function by maintaining fluid balance and correcting metabolic acidosis. It is commonly used in oral rehydration solutions for conditions involving significant fluid loss or risk of acidosis[1][4]. The mechanism of action involves replenishing lost electrolytes (sodium) and buffering acids (citrate), thereby restoring physiological pH balance.