Drug intelligence / Profile preview

sodium chloride + sodium gluconate + magnesium chloride + sodium acetate + potassium chloride

Development stage
Unknown
Lead developer
Takeda
Modality
Small Molecules
Administration
Intravenous
01

Overview

Sodium chloride + sodium gluconate + magnesium chloride + sodium acetate + potassium chloride is a balanced multi-electrolyte crystalloid solution, most commonly represented by **Plasma-Lyte A**. It is a sterile, nonpyrogenic, isotonic intravenous fluid containing sodium, potassium, magnesium, chloride, acetate, and gluconate. The solution restores extracellular water and electrolyte balance; acetate and gluconate are metabolizable bicarbonate precursors that provide an alkalinizing effect. Plasma-Lyte A is used as a source of water and electrolytes and as an alkalinizing agent in adults and pediatric patients. The same ingredient-level description is not fully product-specific, because closely related marketed products include Plasma-Lyte 148, Normosol-R, and the irrigation-only product Physiolyte. ([dailymed.nlm.nih.gov](https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=6ec9e61c-2c26-402f-8604-f446b2e34058))

Brand names
Normosol-RPlasma-Lyte 148Plasma-Lyte148Plasma-Lyte-148Plasma-Lyte APhysiolyte
Other names
Multiple Electrolytes Injection, Type 1, USPmultiple electrolytes solution type 1sodium chloride + sodium gluconate + magnesium chloride + sodium acetate + potassium

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