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Sodium chloride + sodium gluconate + sodium acetate + potassium chloride + magnesium chloride is a balanced, isotonic multi-electrolyte crystalloid solution supplied for intravenous fluid and electrolyte replacement and, in certain products, sterile irrigation. The solution replenishes extracellular water and sodium, potassium, magnesium, chloride, acetate, and gluconate; acetate and gluconate are metabolizable anions that produce an alkalinizing effect through hydrogen-ion consumption during metabolism. Products with this composition include Plasma-Lyte A, Plasma-Lyte 148, Normosol-R, Isolyte S, and the irrigation product Physiolyte. ([dailymed.nlm.nih.gov](https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=6ec9e61c-2c26-402f-8604-f446b2e34058))
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