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sodium chloride + sodium lactate + calcium chloride + magnesium chloride + dextrose monohydrate

Development stage
Approved
Lead developer
Fresenius Medical Care
Modality
Small Molecules
Administration
Intraperitoneal
01

Overview

**Sodium chloride + sodium lactate + calcium chloride + magnesium chloride + dextrose monohydrate** is a peritoneal dialysis solution marketed as **DELFLEX** by Fresenius Medical Care for patients with chronic kidney failure undergoing peritoneal dialysis. It is a sterile hypertonic intraperitoneal solution in which dextrose monohydrate serves as the principal osmotic agent, creating an osmotic gradient across the peritoneal membrane to promote ultrafiltration and removal of water and uremic solutes from the blood, while the electrolyte components help maintain dialysate composition and acid-base balance through lactate buffering. The product has been available in multiple dextrose strengths and electrolyte formulations, including low magnesium and low calcium variants, and is used in the management of chronic kidney failure and historically also acute or chronic renal failure in peritoneal dialysis settings.

Brand names
DELFLEX
Other names
dextrose monohydrate + sodium chloride + sodium lactate + calcium chloride + magnesium chlorideperitoneal dialysis solution

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