Drug intelligence / Profile preview

sodium chloride + sodium lactate + dextrose monohydrate + potassium chloride + calcium chloride

Development stage
Approved
Lead developer
ICU Medical
Modality
Small Molecules
Administration
Intravenous
01

Overview

**Sodium chloride + sodium lactate + dextrose monohydrate + potassium chloride + calcium chloride** is a sterile hypertonic crystalloid intravenous fluid and electrolyte replacement solution, marketed as **Lactated Ringer's and 5% Dextrose Injection**. It supplies water, sodium, chloride, potassium, calcium, lactate, and dextrose for extracellular-volume and electrolyte replacement with modest caloric support. Sodium lactate is metabolized to carbon dioxide and water with consumption of hydrogen ions, producing a metabolic alkalinizing effect; dextrose provides carbohydrate calories and supports blood glucose. The solution is indicated in adults and pediatric patients as a source of water, electrolytes, and calories or as an alkalinizing agent. Each 100 mL contains dextrose hydrous 5 g, sodium chloride 600 mg, sodium lactate anhydrous 310 mg, potassium chloride 30 mg, and calcium chloride dihydrate 20 mg; it has an approximate osmolarity of 525 mOsmol/L and pH 4.0 to 6.5. ([dailymed.nlm.nih.gov](https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=6acc9f96-7088-45a7-b48f-1a861e3467ab))

Brand names
Lactated Ringer's and 5% Dextrose InjectionLactated Ringer's and Dextrose Injection
Other names
dextrose in lactated ringer'slactated ringers and dextroseD5 lactated ringer'sD5LRD-5LRD 5LR

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