Drug intelligence / Profile preview

sodium cromoglycate

Development stage
Approved
Lead developer
Sanofi
Modality
Small Molecules
Administration
Inhalation, Intranasal, Ophthalmic, Oral
01

Overview

Sodium cromoglycate is a synthetic small molecule medication classified as a mast cell stabilizer. It is primarily used for the prophylactic treatment of asthma and allergic conditions such as allergic rhinitis and conjunctivitis. Additionally, it is administered orally to manage systemic mastocytosis and ulcerative colitis. The drug works by inhibiting the degranulation of sensitized mast cells, thereby preventing the release of histamine and other mediators involved in type I allergic reactions. Its mechanism may also involve inhibition of calcium influx into mast cells and possible modulation via G protein-coupled receptor 35 (GPR35). Sodium cromoglycate does not relieve acute asthma attacks but reduces their frequency and severity when used regularly[1][2][8].

Brand names
GastrocromNalcromNasalcrom
Other names
disodium cromoglycatepms-sodium cromoglycate
02

Targets

GPR35 (G-protein Coupled Receptor 35)

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