sodium diatrizoate + sodium picosulfate

Sodium diatrizoate + sodium picosulfate is a combination regimen used for bowel preparation and fecal tagging in computed tomographic colonography (CTC). Sodium diatrizoate is an iodinated, radiopaque contrast medium that serves as a fecal tagging agent; it increases the radiodensity of residual stool, allowing for better differentiation from colonic polyps during imaging. Sodium picosulfate is a stimulant laxative that is hydrolyzed by colonic bacteria into its active metabolite, bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM), which stimulates peristalsis and increases water and electrolyte secretion in the large intestine. This combination is often employed in "minimum-laxative" protocols to improve patient compliance and tolerance compared to high-volume polyethylene glycol (PEG) preparations, while maintaining diagnostic sensitivity for detecting colorectal polyps.

Other names

sodium diatrizoate + sodium picosulfatediatrizoate sodium + sodium picosulfate