sodium feredetate + ascorbic acid

Sodium feredetate + ascorbic acid is a fixed-dose combination iron supplement used for the treatment and prevention of iron deficiency anemia. Sodium feredetate (sodium iron EDTA) is a stable chelated form of iron(III) that protects the iron from precipitating or binding to dietary inhibitors such as phytates and polyphenols in the gastrointestinal tract. This chelation enhances iron bioavailability, particularly in diets high in plant-based inhibitors, and is associated with a lower incidence of gastrointestinal side effects like constipation and nausea compared to traditional ferrous salts. Ascorbic acid (Vitamin C) is included to further enhance iron absorption by acting as a reducing agent, maintaining iron in its more soluble ferrous (Fe2+) state and facilitating its uptake via the divalent metal transporter 1 (DMT1) in the duodenal mucosa.

Brand names

Fero-CFero-C Plus

Other names

sodium iron ethylenediaminetetraacetic acid + ascorbic acidsodium iron EDTA + ascorbic acidsodium iron ethylenediaminetetraacetate + vitamin Csodium feredetate + vitamin C