Drug intelligence / Profile preview

sodium fluoride + potassium nitrate

Development stage
Phase 2
Lead developer
Sheffield Pharmaceuticals
Modality
Small Molecules, Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Hydrogel Systems → Drug Delivery Systems
Administration
Topical, Dental
01

Overview

Sodium fluoride + potassium nitrate is a combination dental product used primarily to prevent dental caries (tooth decay) and to reduce dentinal hypersensitivity (sensitive teeth). Sodium fluoride acts by strengthening tooth enamel and making it more resistant to acid dissolution caused by bacteria. Potassium nitrate works by calming the nerves in the teeth, thereby reducing pain from sensitivity. This combination is typically formulated as a prescription-strength toothpaste or gel containing 1.1% sodium fluoride and 5% potassium nitrate for twice-daily topical use in adults and children over age 12[1][2][3][4][5]. It is not recommended for young children unless directed by a healthcare provider.

Brand names
PreviDent 5000 SensitivePreviDent5000 SensitivePreviDent-5000 SensitivePreviDent 5000 Enamel ProtectPreviDent5000 Enamel ProtectPreviDent-5000 Enamel ProtectSodium Fluoride 5000 PPM SensitiveSodium Fluoride 5000 PPM Enamel Protect
Other names
sodium fluoride and potassium nitratefluoride/potassium nitrate topical

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