Drug intelligence / Profile preview

sodium fluoride + potassium nitrate + isopentane

Development stage
Preclinical
Lead developer
Westminster Pharmaceuticals
Modality
Small Molecules
Administration
Dental
01

Overview

This is an experimental dental formulation combining sodium fluoride (1.1% or 1450 ppm), potassium nitrate (5%), and isopentane (2%). Sodium fluoride works by making teeth stronger and more resistant to decay caused by acid and bacteria. Potassium nitrate works by calming the nerves in the teeth to reduce sensitivity. Isopentane is being investigated as an excipient in dental formulations, though research indicates it neither positively nor negatively affects fluoride efficacy in experimental models.

Brand names
Sensodyne
Other names
Experimental Foaming Gel ToothpasteExperimental gel-to-foam fluoride toothpasteExperimental gel-to-foam NaF toothpaste

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