sodium fluoride + potassium nitrate + sodium bicarbonate

This drug is an investigational combination dentifrice (toothpaste) developed by Church & Dwight, typically formulated with 0.243% sodium fluoride, 5.0% potassium nitrate, and 20% sodium bicarbonate. It is designed for the prevention of dental caries and the treatment of dentin hypersensitivity. Sodium fluoride acts as the primary anticavity agent by promoting the remineralization of tooth enamel and inhibiting the metabolic activity of cariogenic bacteria. Potassium nitrate serves as a desensitizing agent by increasing extracellular potassium ion concentration, which depolarizes and stabilizes dental nerve membranes to block pain transmission. Sodium bicarbonate (baking soda) acts as a mild abrasive for plaque removal and a buffering agent to neutralize acidic plaque environments, further protecting the enamel from demineralization.

Brand names

Arm & Hammer

Other names

Investigational fluoride toothpasteNaF + KNO3 + NaHCO3 dentifrice