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sodium fluoride + sodium monofluorophosphate
- Development stage
- Unknown
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
**Sodium fluoride + sodium monofluorophosphate** is a combination of two anticaries agents widely used in oral healthcare formulations, primarily toothpastes. Both ingredients act as sources of fluoride ions to strengthen dental enamel and prevent tooth decay. - **Sodium fluoride** releases free fluoride ions that aid in remineralization and inhibit the growth of cariogenic bacteria like Streptococcus mutans and lactobacilli[4]. - **Sodium monofluorophosphate** is recognized for its biosafety, can penetrate both surface and deep enamel layers, and helps strengthen acid resistance by delivering fluoride ions[2][5][7]. Both agents together may offer enhanced fluoride delivery and cavity protection, compensating for individual limitations in surface and deep enamel action[2].
- Brand names
- ColgateCrestUltra Brite
- Other names
- disodium phosphorofluoridatephosphorofluoridic acid, disodium salt
02
Targets
HydroxyapatiteOral plaque bacteria
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