Drug intelligence / Profile preview

sodium gluconate

Development stage
Approved
Modality
Small Molecules
Administration
Intravenous, Oral
01

Overview

Sodium gluconate is the sodium salt of gluconic acid, a small molecule compound widely utilized in the pharmaceutical industry primarily as an excipient and occasionally as an active pharmaceutical ingredient (API). As an excipient, it functions as a chelating agent, pH regulator, and stabilizer, helping to maintain the integrity and bioavailability of active ingredients in various formulations. When employed as an API, it serves as a physiological electrolyte agent in large-volume parenteral applications and electrolyte replacement solutions. It is particularly valued for its ability to form stable, water-soluble complexes with divalent and trivalent metal ions, which prevents precipitation and enhances the absorption of minerals like calcium and iron.

Other names
D-gluconic acid monosodium saltmonosodium gluconatesodium D-gluconate
02

Targets

KCNH2 (Voltage-gated potassium channel subfamily H member 2)CYP2C9 (Cytochrome P450 family 2 subfamily C member 9)CYP3A4 (Cytochrome P450 3A4)MG (Mycoplasma gallisepticum)

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