Drug intelligence / Profile preview

sodium glycerophosphate

Development stage
Approved
Lead developer
Fresenius Kabi
Modality
Small Molecules
Administration
Intravenous, Parenteral
01

Overview

**Sodium glycerophosphate** is an injectable organic phosphate replacement product used as a source of phosphate in parenteral nutrition and for treatment or prevention of hypophosphatemia when oral or enteral intake is not possible or insufficient. It is a mineral salt drug rather than a targeted therapeutic; after intravenous admixture into parenteral nutrition, it dissociates and provides bioavailable phosphate for ATP generation, nucleic acid synthesis, phospholipid production, intracellular signaling, and bone mineralization. Public sources verify the asset in Baxter-sponsored Phase 1 bioavailability studies comparing sodium glycerophosphate injection with inorganic phosphate products, and the FDA-approved U.S. product **Glycophos** is labeled for use as a phosphorus source in adults and pediatric patients 12 years and older as part of parenteral nutrition.

Brand names
Glycophos
Other names
sodium glycerophosphate injectionsodium glycerophosphate pentahydrate甘油磷酸钠

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