sodium gualenate

Sodium gualenate is a water-soluble, small molecule derivative of guaiazulene, a natural azulene compound found in chamomile oil. It is primarily utilized for its anti-inflammatory, cytoprotective, and wound-healing properties. The drug acts by protecting the gastric mucosa, inhibiting the release of histamine from mast cells, and suppressing the emigration of leukocytes to sites of inflammation. Clinically, sodium gualenate is indicated for the treatment of gastric and duodenal ulcers, gastritis, and various inflammatory conditions of the oral and pharyngeal cavities, including stomatitis, pharyngitis, and tonsillitis. It is also formulated for ophthalmic use in treating conjunctivitis and blepharitis, and is incorporated into cosmetic products for its skin-conditioning effects.

Brand names

Azunol

Other names

guaiazulene sulfonate sodiumsodium azulene sulfonate薁磺酸钠sodium 1,4-dimethyl-7-isopropylazulene-3-sulfonateguaiazulenesulfonate sodium