Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
sodium hyaluronan butyrate
- Development stage
- Unknown
- Lead developer
- Pontus Pharma
- Modality
- Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Non-biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Injectable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems
- Administration
- Rectal, Topical
01
Overview
Sodium hyaluronan butyrate (also known as sodium butyroyl hyaluronate) is an esterified derivative of hyaluronic acid and butyric acid. It is designed to combine the tissue-repairing, moisturizing, and barrier-forming properties of hyaluronic acid with the anti-inflammatory, antioxidant, and mucosal-healing properties of butyrate. Developed by Sigea and marketed in products like Proctosal by Pontus Pharma, it is formulated as microenemas and topical creams. It is primarily used for the treatment of hemorrhoidal conditions, proctalgia, and the prevention of radiation proctitis in patients undergoing pelvic radiotherapy. By forming a protective mechanical barrier and promoting re-epithelialization, it helps normalize the rectal mucosa and reduce inflammation.
- Brand names
- Proctosal
- Other names
- ITHABUTsodium butyroyl hyaluronatesodium hyaluronate butyrate
02
Targets
CD44 (CD44 antigen)
Beyond the preview
Go deeper on sodium hyaluronan butyrate.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on sodium hyaluronan butyrate.