Drug intelligence / Profile preview

sodium hyaluronate + trehalose + N-acetyl-glucosamine

Development stage
Unknown
Lead developer
Théa Pharmaceuticals
Modality
Small Molecules
Administration
Ophthalmic
01

Overview

This combination product is an ophthalmic solution designed for the management of moderate to severe dry eye syndrome. It combines the hydrating and lubricating properties of **sodium hyaluronate**, a naturally occurring polysaccharide that retains water and stabilizes the tear film, with **trehalose**, a disaccharide that provides bioprotection to the corneal epithelium against desiccation and osmotic stress. The addition of **N-acetyl-glucosamine (NAG)**, a precursor to glycosaminoglycans, is intended to support the repair of the ocular surface and enhance the synthesis of natural hyaluronic acid. Together, these components work synergistically to restore tear film osmolarity, protect the ocular surface from environmental damage, and promote the healing of corneal micro-lesions.

Brand names
Thealoz Duo
Other names
sodium hyaluronate + trehalose + N-acetyl-glucosamine

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