Drug intelligence / Profile preview

sodium hyaluronate + xanthan gum

Development stage
Unknown
Lead developer
SIFI
Modality
Small Molecules
Administration
Ophthalmic
01

Overview

Sodium hyaluronate + xanthan gum is a combined eye gel formulation that contains sodium hyaluronate 0.15% and xanthan gum 1%. This combination leverages the properties of both polysaccharides to create an effective ophthalmic preparation. The formulation accelerates the recovery of corneal epithelial defects and reduces patient complaints when used after procedures such as pterygium surgery. In some commercial products like Xanternet, this combination is supplemented with netilmycine 0.3% to provide additional antimicrobial properties. The combination works through multiple mechanisms: - Sodium hyaluronate provides excellent moisturizing and lubricating properties - Xanthan gum acts as a thickening agent, stabilizer, and suspending agent - Together, they create a gel with pseudoplastic properties that adheres well to the ocular surface - The formulation helps maintain hydration of the corneal epithelium, promoting faster healing

Brand names
Xanternet
Other names
Eyestil Synfo

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