Drug intelligence / Profile preview

sodium hypochlorite + edetic acid + etidronic acid

Development stage: Unknown
Lead developer: Mustafa Kemal University
Modality: Small Molecules
Administration: Topical

Overview

NaOCl + EDTA + HEDP is a combination root canal irrigation regimen used in endodontic procedures, specifically for root canal retreatment in patients with apical periodontitis. Sodium hypochlorite (NaOCl) serves as the primary antimicrobial and tissue-dissolving agent. Etidronic acid (HEDP) is a biocompatible chelating agent that can be mixed directly with NaOCl to provide continuous smear layer removal and enhance antimicrobial efficacy without compromising the stability of the hypochlorite. Ethylenediaminetetraacetic acid (EDTA) is typically used as a final sequential irrigant to ensure complete removal of the inorganic smear layer. This protocol aims to optimize the disinfection of the complex root canal system and improve the success rates of endodontic treatments.

Brand names: DualRinse HEDP
Other names: NaOCl + EDTA + HEDPsodium hypochlorite + EDTA + HEDPsodium hypochlorite + etidronic acid + EDTA

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