Drug intelligence / Profile preview

sodium lactate + calcium chloride + potassium chloride + sodium chloride + dextrose

Development stage
Approved
Lead developer
Pfizer
Modality
Small Molecules
Administration
Intravenous
01

Overview

**Sodium lactate + calcium chloride + potassium chloride + sodium chloride + dextrose** is a fixed-composition intravenous crystalloid solution marketed as Lactated Ringer's and Dextrose (5%) Injection. It combines sodium, potassium, calcium, chloride, lactate, and 5% dextrose to replace extracellular water and electrolytes while providing limited carbohydrate calories. Lactate is metabolized to bicarbonate equivalents and can support alkalinization; the solution has no single pharmacologic receptor target. It is used intravenously in adult and pediatric patients as a source of water, electrolytes, and calories, and as an alkalinizing agent. The labeled formulation contains dextrose 5 g, sodium chloride 600 mg, sodium lactate 310 mg, potassium chloride 30 mg, and calcium chloride 20 mg per 100 mL, and is hypertonic. ([dailymed.nlm.nih.gov](https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=6acc9f96-7088-45a7-b48f-1a861e3467ab))

Other names
lactated ringer's and dextroselactated ringer's and 5% dextrose injectionlactated ringer's and dextrose 5% injectiondextrose in lactated ringer's

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