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sodium lactate + magnesium chloride + sodium chloride + dextrose monohydrate + calcium chloride

Development stage: Approved
Lead developer: Fresenius Medical Care
Modality: Small Molecules
Administration: Intraperitoneal

Overview

A hypertonic **peritoneal dialysis solution** used for peritoneal dialysis in patients with kidney failure. This multi-component electrolyte and carbohydrate formulation contains sodium lactate, magnesium chloride, sodium chloride, dextrose monohydrate, and calcium chloride; dextrose monohydrate serves as the principal osmotic agent, generating an osmotic gradient across the peritoneal membrane to promote ultrafiltration and removal of water and uremic solutes. Sodium lactate functions as a bicarbonate precursor to help correct metabolic acidosis during dialysis. The product is marketed as **DELFLEX** and has been associated with Fresenius Medical Care for manufacture and commercialization. It is administered **intraperitoneally** and is indicated for chronic kidney failure in patients maintained on peritoneal dialysis; related public labeling context also associates this type of solution with acute and chronic renal failure management.

Brand names: DELFLEX
Other names: sodium lactate + magnesium chloride + sodium chloride + dextrose monohydrate + calcium chlorideperitoneal dialysis solutiondelflex peritoneal dialysis solution

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