Drug intelligence / Profile preview

sodium lactate + sodium chloride + calcium chloride + magnesium chloride + dextrose

Development stage
Approved
Lead developer
Baxter Healthcare Corporation
Modality
Small Molecules
Administration
Intraperitoneal
01

Overview

Sodium lactate + sodium chloride + calcium chloride + magnesium chloride + dextrose is a **peritoneal dialysis solution** used intraperitoneally for the management of acute renal failure, chronic renal failure, and chronic kidney failure in patients undergoing continuous ambulatory peritoneal dialysis or automated peritoneal dialysis. Marketed as **DIANEAL** and related formulations, it was originally developed by Baxter Healthcare and is now associated with Vantive and Fresenius Medical Care in U.S. product lineage context. The solution is a **small-molecule electrolyte and carbohydrate formulation** in which dextrose creates an osmotic gradient that promotes ultrafiltration across the peritoneal membrane, while the electrolyte composition helps support fluid and solute exchange during dialysis.

Brand names
DIANEALDIANEAL PD-2DIANEAL LOW CALCIUM WITH DEXTROSE
Other names
sodium lactate + sodium chloride + calcium chloride + magnesium chloride + dextroseperitoneal dialysis solution

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