Drug intelligence / Profile preview

sodium picosulfate + magnesium citrate + bisacodyl

Development stage
Unknown
Lead developer
Ferring Pharmaceuticals
Modality
Small Molecules
Administration
Oral
01

Overview

A combination bowel preparation regimen consisting of sodium picosulfate with magnesium citrate (Pico-Salax) and bisacodyl tablets. Sodium picosulfate is a stimulant laxative that is hydrolyzed by colonic bacteria to form an active metabolite (BHPM) that stimulates colonic peristalsis. Magnesium citrate is an osmotic agent that causes water retention within the gastrointestinal tract. Bisacodyl is a stimulant laxative that works directly on the colon to increase peristalsis. The combination provides enhanced colon cleansing, particularly in the right colon, compared to using Pico-Salax alone or other bowel preparation methods.

Brand names
Pico-Salax plus bisacodyl
Other names
SPMC/bisacodylPSLX plus bisacodyl

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