Drug intelligence / Profile preview

sodium picosulfate + magnesium oxide + citric acid + ascorbic acid

Development stage
Unknown
Lead developer
Gunkang Pharmaceuticals
Modality
Small Molecules
Administration
Oral
01

Overview

원프렙산 (OnePrep 1.38 powder) is an approved oral bowel preparation agent developed by Gunkang Pharmaceuticals and co-marketed with GC Wellbeing. It is classified as an "improved new drug" (개량신약) in South Korea, specifically designed to reduce the total volume of liquid patients must consume before a colonoscopy to 1.38 liters (including the reconstituted drug and additional water). The formulation is a combination of sodium picosulfate, a stimulant laxative that is activated by colonic bacteria; magnesium oxide and citric acid, which react in water to form osmotic magnesium citrate; and ascorbic acid (Vitamin C), which provides additional osmotic activity and improves the safety profile. This combination effectively cleanses the colon while minimizing patient discomfort associated with high-volume preparations.

Brand names
원프렙산OnePrep 1.38 powderOnePrep1.38 powderOnePrep-1.38 powderWonprep 1.38 SanWonprep1.38 SanWonprep-1.38 San
Other names
원프렙 1.38산

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