Drug intelligence / Profile preview

sodium polysulthionate

Development stage
Phase 2
Lead developer
Sulfagenix
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
01

Overview

Sodium polysulthionate is a drug candidate initially developed by Sulfagenix for cardiovascular diseases. It is distinct from sodium polystyrene sulfonate and sodium polysulfide, both of which are unrelated substances with different chemical properties and uses. Sodium polysulthionate has reached Phase 1/2 in clinical development, but detailed information about its mechanism of action, molecular structure, or specific indications within cardiovascular disease remains limited in the public domain[4].

Brand names
SG1002SG-1002SG 1002
Other names
sodium polysulthionatehydrogen sulfide donorH2S prodrugH-2S prodrugH 2S prodrug
02

Targets

CBS (Cystathionine beta-synthase)

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