Drug intelligence / Profile preview

sodium selenite

Development stage
Phase 4
Modality
Small Molecules
Administration
Oral, Intravenous
01

Overview

Sodium selenite is an inorganic compound with the formula Na₂SeO₃. It is a colorless to white crystalline solid that is highly soluble in water. Sodium selenite serves as a source of selenium, an essential trace element required for various biological functions including antioxidant defense and immune support. In medicine and nutrition, it is used as a dietary supplement to treat or prevent selenium deficiency in humans and animals. Mechanistically, it acts as a precursor for the synthesis of essential selenium-containing enzymes such as glutathione peroxidase. Sodium selenite has also been investigated for its potential anticancer properties due1 to its ability to induce apoptosis in certain cancer cells (e.g., prostate cancer, leukemia, melanoma)[1]. Industrially, it finds use in glass manufacturing (to neutralize green iron impurities), agriculture (as a fertilizer additive), animal feed supplementation, and chemical synthesis[2][5][7].

Brand names
Zelnite
Other names
disodium selenitenatriumselenitselenite sodiumbiselenite, sodiummonosodium selenitepentahydrate, sodium seleniteselenite pentahydrate, sodiumselenous acid disodium saltsodium biselenite
02

Targets

GSTO1 (Glutathione S-transferase omega-1)

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