sodium sulfacetamide

Sodium sulfacetamide is a sulfonamide antibiotic small molecule marketed by BioComp Pharma as a generic topical treatment for various dermatological conditions. It functions as a bacteriostatic agent by competitively inhibiting the bacterial enzyme dihydropteroate synthase (DHPS). This action prevents the incorporation of para-aminobenzoic acid (PABA) into dihydropteroic acid, thereby disrupting the synthesis of bacterial folic acid, which is essential for nucleic acid production. BioComp Pharma provides sodium sulfacetamide in several topical dosage forms, including cleansers, lotions, and washes, typically at a 10% concentration. These products are primarily indicated for the treatment of acne vulgaris, acne rosacea, and seborrheic dermatitis. While sodium sulfacetamide is also utilized in ophthalmic formulations for bacterial eye infections, BioComp's portfolio is centered on dermatologic applications.

Brand names

OVACE Plus Lotion

Other names

sulfacetamide sodiumN-Sulfanilylacetamide monosodium salt