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Sodium sulfate/potassium sulfate/magnesium sulfate is an osmotic laxative combination used for cleansing the colon in preparation for colonoscopy in adults. Developed by Braintree Laboratories (now part of Sebela Pharmaceuticals), the formulation consists of poorly absorbed sulfate salts that create an osmotic gradient, drawing water into the intestinal lumen. This increase in water content stimulates peristalsis and results in a watery stool, effectively clearing the bowel of fecal matter to allow for clear visualization during endoscopic procedures. It is typically administered as a split-dose regimen.
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