sodium taurocholate

Sodium taurocholate is the sodium salt of taurocholic acid, a naturally occurring conjugated bile acid formed by the conjugation of cholic acid with taurine. It acts as a physiological detergent, forming micelles that solubilize dietary lipids and fat-soluble vitamins to facilitate their absorption in the gastrointestinal tract. Pharmacologically, sodium taurocholate functions as a choleretic and cholagogue, stimulating bile secretion and flow. It is approved as a key component of normothermic machine perfusion (NMP) systems, such as the OrganOx metra® and TransMedics® Organ Care System (OCS™) Liver, where it is infused into the circulating perfusate to replenish bile salt levels and maintain hepatobiliary viability ex-vivo prior to liver transplantation. Additionally, it is widely used as a research reagent for protein solubilization, lipase activation, and in vitro dissolution testing.

Brand names

AcidobylAlsilineBicholate LilasBicholate Lilas TabBilex TabDuchol EctHerbalax Forte No 70 TabLax-BO TabLaxa TabLaxatif TabLaxativeLaxative TabLaxavite TabMedicholPro Gest TabRegubilTriolax Tab

Other names

acidum cholatauricumcholaic acidcholyltaurinemonosodium N-choloyltaurinatemonosodium taurocholateN-choloyltaurineN-choloyltaurine sodiumsodium N-choloyltaurinatetaurocholate sodiumtaurocholate sodium salttaurocholic acidtaurocholic acid sodium salt