Drug intelligence / Profile preview

sodium trimetaphosphate

Development stage
Unknown
Lead developer
ICL Group
Modality
Small Molecules
Administration
Topical
01

Overview

Sodium trimetaphosphate (STMP) is an inorganic cyclic polyphosphate primarily utilized in oral healthcare for its potent anti-caries and remineralizing properties. In dental applications, STMP functions by adsorbing onto the hydroxyapatite surface of tooth enamel, where it acts as a protective barrier against acid-mediated demineralization and enhances the efficacy of fluoride by promoting the deposition of calcium and phosphate ions from saliva. Beyond dentistry, STMP is widely employed as a cross-linking agent in the development of biocompatible hydrogels and modified starch excipients for controlled-release drug delivery systems. Its ability to modify the surface charge and reactivity of biological substrates makes it a valuable component in both preventative medicine and pharmaceutical engineering.

Other names
trisodium trimetaphosphatecyclotriphosphate trisodium saltsodium cyclotriphosphatetrimetaphosphoric acid trisodium salt

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