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sogyeonghwalhyeol-tang

Development stage: Phase 4
Lead developer: Gachon University Gil Oriental Medical Hospital
Modality: Small Molecules
Administration: Oral

Overview

Sogyeonghwalhyeol-tang (SGHH) is a traditional East Asian polyherbal formula composed of 17 medicinal herbs, widely used in Korean and Chinese medicine for its analgesic and anti-inflammatory properties. It is primarily indicated for musculoskeletal conditions such as chronic low back pain, neuralgia, and arthritis. The formula is traditionally believed to improve blood circulation and expel 'wind-dampness' and 'blood stasis.' Modern pharmacological research suggests that SGHH exerts its therapeutic effects by inhibiting pro-inflammatory cytokines and mediators, including COX-2, TNF-alpha, and IL-6. Recent clinical and observational studies have also explored its potential in reducing cardiovascular disease risk in patients with systemic lupus erythematosus (SLE).

Other names: Shu-Jing-Huo-Xue-TangSokeikakketsutoSo-Kyung-Hwal-Hyeol-TangSJHXT

Targets

TNFA (Tumor necrosis factor alpha (soluble))IL-6 (Interleukin 6)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)

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