Drug intelligence / Profile preview

Solrikitug-Based Bispecific 2

Development stage
Preclinical
Lead developer
Uniquity Bio
Modality
Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
Administration
Subcutaneous
01

Overview

Solrikitug-Based Bispecific 2 is a preclinical bispecific antibody being developed by Uniquity Bio. It is constructed using solrikitug, a monoclonal antibody that targets Thymic Stromal Lymphopoietin (TSLP), as a foundational component. The molecule is designed to bind both TSLP and a second, undisclosed target to modulate immune and inflammatory pathways. TSLP is an epithelial-derived cytokine that acts as a master regulator of type 2 (T2) inflammation and is implicated in various respiratory and gastrointestinal diseases. By targeting two distinct pathways, this bispecific antibody aims to provide enhanced therapeutic efficacy over TSLP inhibition alone. The program is currently in the preclinical stage for undisclosed indications within the immunology and inflammation therapeutic area.

02

Targets

TSLP (Thymic stromal lymphopoietin)

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