Somaiya Vidyavihar Univ. EGFR compound AE4

Somaiya Vidyavihar Univ. EGFR compound AE4: sourced facts only. name: "In vitro EGFR kinase assays confirmed their inhibition, with IC50 values of 3.95 µM (AE4), 3.49 µM (AE11), and 4.45 µM (AF11), selectively reduced p-EGFR Tyr1068 and ERK1/2 levels in a dose-dependent manner, while inducing G0/G1 cell-cycle arrest and apoptosis." [PMID:42853331]; target: "In vitro EGFR kinase assays confirmed their inhibition, with IC50 values of 3.95 µM (AE4), 3.49 µM (AE11), and 4.45 µM (AF11), selectively reduced p-EGFR Tyr1068 and ERK1/2 levels in a dose-dependent manner, while inducing G0/G1 cell-cycle arrest and apoptosis." [PMID:42853331]; developer: "Somaiya Institute for Research and Consultancy, Somaiya Vidyavihar University, Vidyavihar (East), Mumbai, India." [PMID:42853331]